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. 2017 Mar 6;8:95. doi: 10.3389/fphar.2017.00095

FIGURE 4.

FIGURE 4

Schematic illustration of the mPFC recording sites which are indicated by filled circles. Number values in mm indicate distance from bregma (A). Representative schematic illustration showing the location of the recording electrode in cortex and of the stimulation electrode in the BLA. Number values refer to stimulation parameters (B). BLA electrical stimulation evokes excitatory [BLA → mPFC(+)] or inhibitory [BLA → PLC(–)] responses in different mPFC neuron populations. (C,D,F,G,I,J) Show peristimulus time histograms (PSTHs) of SHAM (C,D), TBI 14 days (F,G) and TBI 60 days mice (I,J) receiving subcutaneous vehicle injection. PSTHs show responses of a single neuron to a pulse (200 μA intensity, black arrows) delivered at in the BLA at 0.5-Hz stimulation (vertical bar). Representative average waveforms of SHAM (E), TBI 14 days (H), and TBI 60 days mice (K). Horizontal bar = 1 ms; vertical bar = 200 mV.