Figure 1.
Combined flavonoids on hematological parameters in anemic rats. Rats were injected with sterile water or with CYP (25 mg·kg−1) for 4 days. Then, the rats were divided into five groups. Normal: normal rats treated with sterile water (normal); Control: CYP‐treated rats with saline; EPO: CYP‐treated rats with EPO (75 IU·kg−1·day−1 body weight); CF: CYP‐treated rats with low dose (11.2 μmol·kg−1·day−1) or with a high dose of flavonoid combination (32 μmol·kg−1·day−1). The flavonoid mixture (32 μmol), containing 4 μmol formononetin, 4 μmol ononin, 20 μmol calycosin, and 4 μmol calycosin‐7‐O‐β‐d‐glucoside, was dissolved in saline. The number of red blood cell (RBC), white blood cell (WBC), amount of hemoglobin, and the percentage of hematocrit were determined. Data are expressed as Mean ± SD, where n = 6–8. [*] where P < 0.05; [**] where P < 0.01 and; [***] where P < 0.001 as compared with control group.