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. 2015 Oct 5;30(3):309–319. doi: 10.5713/ajas.15.0608

Table 2.

Significant genetic regions in GWAS results of milk fat

CHR Region ID regDIS p-value Bonferroni SNP ID SNP Pos SNP p-value Ensembl gene ID (Gene symbol) QTL trait
2 CHR2:78302162 131569 1.78E-08 1.46.E-04 Hapmap26185-BTA-157573 78302162 3.41.E-03
-78433731 Hapmap40841-BTA-94957 78332368 2.18.E-03
BTB-01945480 78366932 2.06.E-03
BTB-01767882 78405537 9.17.E-03
BTB-01767855 78433731 4.18.E-03
2 CHR2:78691609 201692 3.05E-06 2.50.E-02 BTB-01860738 78691609 5.29.E-04
-78893301 BTB-01860839 78726622 2.13.E-01
BTB-00103543 78749162 1.08.E-01
BTB-01374180 78872254 3.80.E-03
BTB-01374162 78893301 5.49.E-03
2 CHR2:80605588 396947 1.15E-06 9.45.E-03 ARS-BFGL-NGS-41490 80605588 6.49.E-02 ENSBTAG00000014832 (TMEFF2)
-81002535 ARS-BFGL-NGS-5680 80666057 1.92.E-02 ENSBTAG00000046400
Hapmap50262-BTA-122131 80687709 4.03.E-02 ENSBTAG00000018653 (NABP1)
ARS-BFGL-NGS-94696 80970515 1.89.E-03 ENSBTAG00000018497 (SDPR)
ARS-BFGL-NGS-102243 81002535 8.33.E-04
2 CHR2:86831095 173378 5.21E-06 4.27.E-02 BTA-90292-no-rs 86831095 6.92.E-01 ENSBTAG00000007635 (PLCL1) Meat_and_Carcass_Association
-87004473 BTA-90298-no-rs 86868918 2.31.E-01 (Intermuscular fat percentage: QTLID25126)
Hapmap38934-BTA-117244 86909355 2.24.E-03 Meat_and_Carcass_Association
Hapmap41106-BTA-90288 86959111 2.79.E-03 (Subcutaneous fat: QTLID25127)
ARS-BFGL-NGS-55270 87004473 4.87.E-04 Meat_and_Carcass_Association
(Intermuscular fat percentage: QTLID25128)
Exterior_Association
(Udder structure: QTLID25015)
Milk_Association
(Milk fat percentage: QTLID25003)
Exterior_Association
(Udder structure: QTLID25017)
3 CHR3:69182813 208532 1.17E-06 9.61.E-03 BTB-01635025 69182813 3.76.E-01 ENSBTAG00000042950 (SNORD45)
-69391345 BTB-00133734 69292666 6.16.E-03 ENSBTAG00000024240 (ACADM)
BTB-00133701 69315385 1.54.E-03 ENSBTAG00000005864 (ASB17)
BTB-00133671 69342335 6.32.E-03 ENSBTAG00000043447 (SNORD45)
BTB-01711286 69391345 3.58.E-03 ENSBTAG00000018447 (RABGGTB)
ENSBTAG00000018448 (MSH4)
ENSBTAG00000042353 (SNORD45)
15 CHR15:67269656 159969 9.74E-08 8.00.E-04 ARS-BFGL-NGS-36801 67269656 5.86.E-02 ENSBTAG00000044158 Reproduction_QTL
-67429625 ARS-BFGL-NGS-111525 67323237 1.94.E-03 (LDLRAD3)
Hapmap41218-BTA-28547 67358867 3.53.E-03 (Calving ease (direct) : QTLID15193)
ARS-BFGL-NGS-92508 67386416 3.68.E-05 Reproduction_QTL
BTB-00611649 67429625 2.88.E-01 (Calving index: QTLID15194)
Reproduction_QTL
(Calving ease (maternal) : QTLID15192)
Production_QTL
(Average Daily Gain: QTLID22798)

GWAS, genome-wide association studies; CHR, chromosome; SNP, single nucleotide polymorphism; QTL, quantitative trait locus.