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. 2017 Mar 6;7:43570. doi: 10.1038/srep43570

Figure 3. ENM-mediated mast cell degranulation.

Figure 3

Bone marrow-derived mast cells (BMMCs) were exposed to ENMs for 1 h and evaluated for the release of β-hexosaminidase into the supernatant. (a) BMMCs were exposed to (a) mass concentrations of ENMs (50 μg/ml) or DNP (100 ng/ml) as an IgE positive control and (c) ENMs normalized to surface area (20 m2/g). Values are expressed as mean ± SEM normalized to non-treated control group (n = 3/group). *Indicates significant difference from non-treated control group (p ≤ 0.05).