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. 2017 Mar 6;7:43639. doi: 10.1038/srep43639

Figure 5. Both genetic and chemical Pin1 inhibition blocks multiple cancer-driving pathways simultaneously in human HCC cells.

Figure 5

PLC/PRF/5 or Huh-7 cell lines were infected with lentivirus expressing scrambled or Pin1 shRNA (A), or treated with 10 μM ATRA (PLC/PRF/5) or 10 μM ATRA combined with 25 μM liarozole (Huh-7) (B). Cell lysates were subjected to Western blot analysis with specific antibodies.