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. 2017 Mar 6;7:43474. doi: 10.1038/srep43474

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Copyright © 2017, The Author(s)

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The dissected intrascapular BAT depot of alcohol fed mice is visibly smaller (A). Body weight was not changed in mice chronically consuming alcohol (B); however, BAT weight was significantly decreased throughout the alcohol feeding period, which was verified by analyzing the BAT:Body weight ratio (E). There was no significant change in the weight of the epididymal white adipose tissue (WAT) depot weight (D). Follow-up studies show that alcohol’s ability to decrease BAT mass occurs independently of dietary fat content, or genetic background (F). (B–E) analyzed by one-way ANOVA; bars with different letters are significantly different; p < 0.05. (F) analyzed by Student’s t-test; *p < 0.05. Sample size: (B–E), control n = 12, all alcohol groups n = 6; (F) all groups n = 5–6.