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. 2017 Mar 6;7:43702. doi: 10.1038/srep43702

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Panel (A) shows BrdU-positive cells in small intestinal crypts (brown staining). (B) Quantification of the proportion of BrdU-positive cells per intestinal crypt column. A minimum of 20 crypt columns were counted per animal. Panel (C) shows BrdU-positive cells in a representative small intestinal tumor, and quantification of the proportion of BrdU-positive cells is shown in panel (D). Five animals per group were scored. A minimum of 3 tumors per animal and at least 350 total cells per tumor were scored blinded from the animal ID. No significant differences were observed (Student’s t-test p > 0.05). N = number of animals.