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. 2017 Mar 6;7:43470. doi: 10.1038/srep43470

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Analyses of relative aggrecan (A), brevican (B) and phosphacan/RPTPβ/ζ (RPTPβ/ζ CA and RPTPβ/ζ PTP1 primer pairs, C,D) mRNA expression using qRT-PCR in optic nerves of control (CO) and ischemic (I/R) eyes. Our expression analysis revealed a significant upregulation of brevican and phosphacan/RPTPβ/ζ in the optic nerve following ischemia. A comparable mRNA expression level was observed for aggrecan in both groups. Values are median ± quartile ± maximum/minimum. *p ≤ 0.05; **p ≤ 0.01; n = 4/group.