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Long-term oral glucose tolerance tests (a) of Nopal water extract (NPWE) after 12 h food deprivation in STZ-induced SD rats fed a high-fat diet. (b) Area under the blood glucose concentration curve was measured over 180 min (AUC-180 min). Values are expressed as the mean ± SE (n = 10). Different letters in the same time (a) show statistically significant differences, P < 0.05. ∗∗∗P < 0.001 versus HF-STZ-Control.
