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. 2016 Jun 3;82(3):773–783. doi: 10.1111/bcp.12989

Figure 3.

Figure 3

Visual predictive check plots for the pharmacokinetic model of doxorubicin (doxo) (A) and doxorubicinol (doxo'ol) (B), and the PK‐PD model of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) (C). Circles represent observations. Lines represent 5th (dashed), 50th (solid) and 95th (dashed) percentiles of observations; and shaded areas represent the 95% confidence intervals of the 5th, 50th and 95th quantiles of the simulated data sets from the model