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. 2016 Apr 25;83(1):8–19. doi: 10.1111/bcp.12935

Table 2.

Examples of normal constituents of the diet or enzymes used as dietary supplements to treat or prevent illnesses or diseases associated with deficiencies

Compound Deficiency disease
Normal dietary constitutents
Carnitine Primary deficiency 24; valproate toxicity 25
Cereal starch Glycogen storage disease 26
Cobalamins Pernicious anaemia 27
Ferrous salts Iron deficiency anaemia 28
Folic acid * Folate deficiency 29
Vitamin C Scurvy 30
Vitamin D analogues Osteomalacia and rickets 31
Zinc Acrodermatitis enteropathica 32
Enzymes 33
Agalsidase Fabry's disease
Alglucosidase alfa Pompe's disease
Galsulfase Mucopolysaccharidosis type VI
Idursulfase Mucopolysaccharidosis type II
Imiglucerase Gaucher's disease types I and III
Lactase Lactose intolerance 34
Laronidase Mucopolysaccharidosis type I
Pancreatic enzymes Exocrine pancreatic insufficiency 35
Velaglucerase alfa Gaucher's disease type I
*

Also used in pregnancy to prevent neural tube defects, a use that is not relevant to this table.