Table 2.
Compound | Deficiency disease |
---|---|
Normal dietary constitutents | |
Carnitine | Primary deficiency 24; valproate toxicity 25 |
Cereal starch | Glycogen storage disease 26 |
Cobalamins | Pernicious anaemia 27 |
Ferrous salts | Iron deficiency anaemia 28 |
Folic acid * | Folate deficiency 29 |
Vitamin C | Scurvy 30 |
Vitamin D analogues | Osteomalacia and rickets 31 |
Zinc | Acrodermatitis enteropathica 32 |
Enzymes 33 | |
Agalsidase | Fabry's disease |
Alglucosidase alfa | Pompe's disease |
Galsulfase | Mucopolysaccharidosis type VI |
Idursulfase | Mucopolysaccharidosis type II |
Imiglucerase | Gaucher's disease types I and III |
Lactase | Lactose intolerance 34 |
Laronidase | Mucopolysaccharidosis type I |
Pancreatic enzymes | Exocrine pancreatic insufficiency 35 |
Velaglucerase alfa | Gaucher's disease type I |
Also used in pregnancy to prevent neural tube defects, a use that is not relevant to this table.