Table 1. Demographic and clinical data of the cohorts of WP1-UK-ER*.
Control Children | Asthma Children | |
---|---|---|
Number of subjects | 21 | 24 |
Gender | 12 (M) = 57% 9 (F) = 42,8% | 15 (M) = 62,5% 9 (F) = 37,5% |
Age [years] | 4,7 ± 0,18 | 4,9 ± 0,1 |
Skin Prick Test positive | 25% (2/8) | 77% (17/22)*** |
Average age at onset of symptoms [years] | — | 2,2 |
**FEV1 < 100% | 23,8% (5/21) | 54% (13/24) |
Allergic Rhinitis | 0 | 33% (8/24) |
Atopic eczema | 4,76% (1/21) | 4% (1/24) |
Allergic rhinitis and atopic eczema | 0 | 38% (9/24) |
without allergic co-morbidity | 95% (20/21) | 25% (6/24) |
family predisposition to asthma | 14% (3/21 maternal) | 38% (9/24) |
family predisposition to atopy | 76% (16/21) | 83% (20/24) |
both parents with atopy | 23,8% (5/21) | 46% (11/24) |
without family predisposition | 23% (5/21) | 17% (4/24) |
*WP1-UK-ER = Work Package 1 within the PreDicta Study at the Universitätsklinikum Erlangen and the University of Erlangen-Nürnberg; **FEV1 = Forced Expiratory Volume in 1 second; ***2 children: skin prick test not done.