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Depleting the Ndc80 complex does not cause centromere DNA instability. (A) Quantification of micronuclei in hTERT-RPE1 cells, treated with control siRNA (siCNT) or siRNA targeting to Hec1 for 72 h. Error bars ± SD, ***P ≤ 0.0005. (B) Quantification of aberrant c-CO-FISH pattern. n = 13. Error bars ± SD. Ns, nonsignificant.
