Fig. 2.

Stretchable living sensors can independently detect multiple chemicals. (A) Schematic illustration of a hydrogel–elastomer hybrid with four isolated chambers to host bacterial strains, including DAPG_RCV/GFP, AHL_RCV/GFP, IPTG_RCV/GFP, and Rham_RCV/GFP. Signaling molecules were diffused from the environment through the hydrogel window into cell chambers, where they were detected by the bacteria. (B) Genetic circuits were constructed in bacterial strains to detect cognate inducers (i.e., DAPG, AHL, IPTG, and Rham) and produce GFP. (C) Images of living devices after exposure to individual or multiple inputs. Cell chambers hosting bacteria with the cognate sensors showed green fluorescence, whereas the noncognate bacteria in chambers were not fluorescent. Scale bars are shown in images.