Fig. 5.

Schematic of the nucleation pathway of lysozyme crystals. Initially, the lysozyme molecules and the ASPs are in the bulk solution. The pathway where molecules assemble into a crystal was not observed. The transformation from the ASP to a crystal was also not observed. Instead, molecules were assembled into noncrystalline particles, for which the detailed features remain undetermined, which heterogeneously nucleate on the container walls or sometimes on the surface of the ASPs. Crystal nucleation was observed only via the noncrystalline particles.