Fig. S8.

Evaluation of concentration variations around a growing particle. (A) Schematic of the model geometry. A particle of radius r (shown in green) nucleates and grows with the observed growth rate. The volume of the growth solution that contributes to the crystal growth is defined by the diffusion length $l=\sqrt{Dt}$, where D is the diffusivity of the lysozyme molecule in the growth solution, which is 1.1 × 10⁻¹⁰ m²⋅s^–1 (34). The thickness of the growth cell is 500 nm. (B) The evolution of the lysozyme concentration C* in contributing growth solution for 8 s after nucleation. The largest decrease in C* is 0.05% for an initial concentration of 15 mg⋅mL^–1. This decrement should decrease the growth rate by only 0.04 nm⋅s^–1.