Table 1.

Plasmid-only based reverse genetics systems of selected RNA viruses

Virus	Genomic RNA	Virus family	Lead publication
Poliovirus	ss(+)RNA	Picornaviridae	Racaniello and Baltimore (3)
Astrovirus	ss(+)RNA	Astroviridae	Geigenmueller et al. (4)
Mouse norovirus	ss(+)RNA	Caliciviridae	Chaudhry et al. (5)
HIV	ss(+)RNA dim rev tr	Retroviridae	Sadaie et al. (6)
HCV	ss(+)RNA	Flaviviridae	Wakita et al. (7)
Influenza A virus	ss(−)RNA 8 seg	Orthomyxoviridae	Fodor et al. (8); Neumann et al. (9)
Bunyavirus	ss(−/+)RNA 3 seg	Bunyaviridae	Bridgen and Elliott (10)
IBDV	dsRNA 2 seg	Birnaviridae	Mundt and Vakharia (11)
Reovirus	dsRNA 10 seg	Reoviridae	Kobayashi et al. (12)
BTV	dsRNA 10 seg	Reoviridae	Boyce et al. (13)
Rotavirus	dsRNA 11 seg	Reoviridae	Kanai et al. (1)

A more comprehensive list (up to 2005) is presented in table S1 of Kobayashi et al. (12). BTV, bluetongue virus; dim rev tr, dimeric reverse transcribing; ds, double stranded; HCV, hepatitis C virus; HIV, human immunodeficiency virus; IBDV, infectious bursal disease virus; seg, number of segments; ss, single-stranded; +/−, of positive or negative sense.