Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 13;114(9):2373–2378. doi: 10.1073/pnas.1618354114

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 4. — Down-regulation of CG13646 transcripts elevates level of aggression. (A) Heterozygous P-element mutants of CG13646 began fights significantly earlier (Wilcoxon test, P = 0.002) and (B) lunged significantly more (Wilcoxon test, P = 0.03) than control flies (n = 23–27). (C) Heterozygous mutants won significantly more fights (χ² test, P = 0.001, n = 32) against wild-type Canton-S flies (first bar) than did control flies (second bar, χ² test, P = 1.0, n = 28). (D) Flies with pan-neuronal knockdown using RNAi of CG13646 (elav^c155-Gal4;UAS-dcr2;UAS-CG13646^RNAi) began fights significantly earlier than both control lines (elav^c155-Gal4;UAS-dcr2/+ and elav^c155-Gal4;UAS-dcr2;UAS-chorion protein^RNAi) (Wilcoxon test, P < 0.005). (E) RNAi knockdown of CG13646 flies also lunge significantly more than attP40 (Wilcoxon test, P = 0.004) and chorion protein RNAi (Wilcoxon test, P < 0.001) control flies (n = 22–26). (F) Pan-neuronal knockdown of CG13646 yielded flies that were significantly more likely to win dyadic fights against attP40 control flies (elav^c155-Gal4;UAS-dcr2/+) (χ² test, P = 0.01, n = 21), whereas flies in the RNAi control group (elav^c155-Gal4;UAS-dcr2;UAS-chorion protein^RNAi) had no significant advantage on the outcome of fights (χ² test, P = 0.68, n = 24).