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. 2016 Dec 8;312(2):G133–G144. doi: 10.1152/ajpgi.00325.2016

Fig. 2.

Fig. 2.

Notch inhibition reduces progenitor cell proliferation in the corpus epithelium. A: body weight (calculated as % initial weight) was measured in vehicle- (n = 26), DBZ- (n = 28), Gd- (n = 4), N1- (n = 7), N2- (n = 7), and N1/N2-treated (n = 7) animals each day before tissue collection on day 6. Data are presented as means ± SE *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. control using two-way ANOVA. B, C, and E–H: paraffin sections from each group in A were stained for Ki67 to examine cellular proliferation. Hematoxylin was used as a nuclear counterstain. D: morphometric quantification of Ki67+ cells. Data are presented as means ± SE (n = 3–5 mice/group). *P < 0.05 vs. vehicle using Student’s t-test; *P < 0.05, ***P < 0.001 vs. Gd using one-way ANOVA. Scale bars: 50 μm.