Table 1.
Variable |
BMI<25
(n=195) |
BMI 25-30
(n=551) |
BMI 30-35
(n=482) |
BMI >35
(n=424) |
P |
---|---|---|---|---|---|
Age, years | 59.7 ± 10.7 | 60.4 ± 10.4 | 59.3 ± 10.2 | 57.6 ± 10.1 | 0.71 |
Females | 57 | 51 | 63 | 80 | <0.0001 |
CVD | 6.7 | 7.1 | 9.1 | 8 | 0.59 |
Ever Smoked | 36.4 | 28.3 | 27.6 | 24.3 | 0.02 |
Hypertension | 59.4 | 72.6 | 75.2 | 81.5 | <0.0001 |
Diabetes mellitus | 7.8 | 21.4 | 28.2 | 40.3 | <0.0001 |
Anti-HTN med* | 52 | 65 | 68 | 77 | <0.0001 |
Anti-diabetic med* | 7 | 17 | 22 | 29 | <0.0001 |
Statin * | 23 | 27 | 27 | 24 | 0.52 |
Heart rate, bpm | 71 ± 12 | 70 ± 11 | 70 ± 10 | 73 ± 13 | <0.0001 |
Systolic BP, mm Hg | 127 ± 19 | 126 ± 16 | 126 ± 18 | 128 ± 20 | <0.0001 |
Diastolic BP, mm Hg | 75 ± 10 | 75 ± 11 | 76 ± 11 | 80 ± 46 | <0.0001 |
Fasting glucose*, mg/dL | 94 ± 21 | 103 ± 34 | 105 ± 33 | 110 ± 39 | <0.0001 |
Total Chol.*, mg/dL | 202 ± 39 | 197 ± 40 | 199 ± 40 | 196 ± 42 | 0.37 |
LDL*, mg/dL | 119 ± 36 | 120 ± 36 | 124 ± 36 | 121 ± 37 | 0.88 |
Triglyceride*, mg/dL | 87 ± 58 | 95 ± 59 | 102 ± 62 | 100 ± 65 | 0.16 |
eGFR*, ml/min/1.73m2 | 91 ± 20 | 88 ± 20 | 89 ± 21 | 91 ± 23 | 0.008 |
Chronic Kidney Disease | 6.5 | 7.5 | 7.7 | 10.8 | 0.24 |
HOMA-IR y, units | 1.70 ± 1.33 | 2.44 ± 1.56 | 3.35 ± 1.88 | 3.87 ± 2.12 | <0.0001 |
CRP, mg/mL | 0.28 ± 0.52 | 0.33 ± 0.53 | 0.50 ± 0.60 | 0.93 ± 1.58 | <0.0001 |
P-Selectin, ng/mL | 31.8 ± 11.0 | 32.1 ± 10.7 | 34.0 ± 11.7 | 34.3 ± 11.4 | 0.29 |
E-selectin, ng/mL | 38.6 ± 17.0 | 41.5 ± 18.7 | 43.9 ± 18.3 | 46.9 ± 21.6 | <0.0001 |
VAT (cm3) z | 547 ± 283 | 657 ± 250 | 896 ± 364 | 987 ± 409 | <0.0001 |
Data presented as mean ± SD or percentage.
>5% of participants missing.
only available for non diabetics.
only available for 246 participants from visit 2.