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. 2016 Aug 23;12(3):546–552. doi: 10.2215/CJN.02430316

Figure 4.

Figure 4.

Causal diagrams that represent three possible relationships between smoking, ESRD, and albumin-to-creatinine ratio (ACR) in the Study of Heart and Renal Protection. (A) ACR is an effect mediator on the causal pathway between smoking and ESRD. (B) ACR is a collider on one the paths between smoking and ESRD. (C) ACR is an effect mediator on one path and a collider on another path between smoking and ESRD.