Table 2.
Risk of hypertension among stone formers compared with controls
| Adjusting Factors | Hazard Ratio (95% Confidence Interval) | P Value |
|---|---|---|
| None | 1.50 (1.18 to 1.92) | 0.001 |
| Age and sex | 1.53 (1.20 to 1.96) | <0.001 |
| Age, sex, and BMI | 1.49 (1.17 to 1.90) | 0.001 |
| Age, sex, BMI, baseline serum creatinine, diabetes mellitus, gout, coronary artery disease, dyslipidemia, tobacco use, and alcohol abuse | 1.44 (1.13 to 1.84) | 0.004 |
| Age, sex BMI, CKD,a and serum creatininea | 1.56 (1.12 to 2.18) | <0.01 |
| Age, sex, BMI, diabetes mellitus, gout, coronary artery disease, dyslipidemia, tobacco use, alcohol abuse, CKD,a and serum creatininea | 1.58 (1.12 to 2.21) | <0.01 |
| Age, sex, and BMI (excluding those who ever used thiazide diuretics) | 1.65 (1.16 to 2.38) | <0.01 |
| Age, sex, BMI, diabetes mellitus, gout, coronary artery disease, dyslipidemia, tobacco use, alcohol abuse, CKD,a and serum creatininea (excluding those who ever used thiazide diuretics) | 1.71 (1.07 to 2.74) | 0.03 |
BMI, body mass index.
a
Serum creatinine and clinically diagnosed CKD were modeled as a time-dependent covariates; 95% of stone formers and 91% of controls had at least one serum creatinine level.