Figure 3.

Frequency graphs of the trial efficacy endpoints and dopamine infusion time displayed an effective treatment duration of around 7.1 hours which was achieved only in one third of donors assigned to dopamine. Cumulative percentage frequency of (A) freedom from multiple dialyses requirement immediately after transplantation, and (B) survival with functioning graft 5 years after transplantation, by dopamine infusion time. Vertical dashed lines denote the infusion time at the inflection point. (C) Frequency distribution of dopamine infusion time. (D) Adjusted hazard ratios (HR) of all-cause graft failure 5 years after transplantation and related 95% confidence intervals (95% CI) according to rising thresholds of exposure to the continuous dopamine infusion.