Table 4.

Multiple Cox regression of all-cause graft failure taking infusion time ≥7.1 h as cut-off value

Variable	HR	95% Confidence Interval	P Value
Dopamine infusion time ≥7.1 h	0.52	0.29 to 0.94	0.03
Donor age, yr	1.02	1.00 to 1.04	0.01
Female donor	1.03	0.71 to 1.50	0.88
Donor systolic BP, mmHg	1.00	0.99 to 1.01	0.93
Donor diastolic BP, mmHg	1.00	0.98 to 1.02	0.99
Donor urine production last h, ml	1.00	0.998 to 1.001	0.79
Head trauma, yes	1.20	0.74 to 1.94	0.46
Cerebral stroke, yes	0.89	0.49 to 1.61	0.69
Cerebral ischemia/cerebral edema, yes	0.42	0.18 to 1.00	0.05
Time from admission on ICU to brain-death confirmation, d	1.01	0.97 to 1.05	0.65
Time from brain-death confirmation to organ procurement, h	1.00	0.96 to 1.05	0.86
Multiorgan versus kidney-only donor, yes	1.02	0.67 to 1.55	0.93
Cold ischemic time, h	1.01	0.97 to 1.04	0.72
Recipient age, yr	1.03	1.01 to 1.05	0.001
Female recipient	1.34	0.91 to 1.99	0.14
Recipient weight, kg	1.01	0.99 to 1.02	0.14
Recipient diabetes, yes	1.86	1.10 to 3.12	0.02
Time spent on waiting list, yr	1.00	0.94 to 1.07	0.95
Antigen mismatches A, B, and DR, n	1.05	0.93 to 1.18	0.45
Panel reactive antibody >5%, yes	1.22	0.70 to 2.14	0.48
Repeat transplant, yes	2.10	1.28 to 3.46	0.003
Induction therapy, yes	0.84	0.59 to 1.19	0.33
Tacrolimus versus cyclosporinea	0.78	0.53 to 1.14	0.20

Analyses cover the entire trial cohort including control patients. HR, hazard ratio; ICU, intensive care unit.

^aAt time of transplantation.