Skip to main content
. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Toxicology. 2016 Dec 31;377:73–80. doi: 10.1016/j.tox.2016.12.009

Figure 4. Lymphocytes contribute to biliary fibrosis in ANIT-exposed mice.

Figure 4

Wild-type (WT) and RAG1−/− mice were fed standard control rodent chow or diet containing 0.05% ANIT for 4 weeks. Representative photomicrographs show liver sections stained for CK-19 (brown) and Sirius red (red) at (A) 100× (scale bar 500 microns) and (B) 200× (scale bar 100 microns). (C) Sirius red staining was quantified as described in Materials and Methods. (D) Area of sirius red-staining expressed as a ratio of CK-19-positive staining. Data are expressed as mean + SEM; n=5–10 mice per group. *p<0.05 vs. control diet. #p<0.05 vs. ANIT-exposed WT mice.