. 2017 Mar 6;12(3):e0173200. doi: 10.1371/journal.pone.0173200

Table 2. Model-based indexes in ZLR and ZFR groups.

	INSULIN SENSITIVITY	FIRST-PHASE β-CELL RESPONSIVENESS	SECOND-PHASE β-CELL RESPONSIVENESS
	S_I	Φ₁	Φ₂
ZLR	1.7 [1] (20%)	186 ± 13 (22%)	1.60 [1.47] (37%)
ZFR	0.3 [0.1] (28%)	661 ± 98 (19%)	7.87 ± 0.52 (37%)
Statistics	P < 0.001^**	P < 0.001^*	P < 0.001^**

ZLR, Zucker Lean Rat; ZFR, Zucker Fatty Rat; S_I (10⁻⁴·min^-1/(pmol·L^-1)); Φ₁ ((pmol/L C-peptide)/(mmol/L glucose)); Φ₂ (10⁻¹ min^-2·(pmol/L C-peptide)/(mmol/L glucose)). Values are reported as means ± SE or as median [IQR]. The percent coefficient of variation of the estimates (CV%) was given in parentheses.

* Unpaired Student’s t-test;

** Wilcoxon rank sum test.