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360˚ rotation of a 45 μm thick Z-stack depicting the spatial distribution of human CD4+ T-cells (magenta), HIV-1 p24 (green), human CD8+ T-cells (red) and nuclei (blue) in colon at 12-days PI. Crypts are at the base and villus tips extend toward the top of the volume. Quantification of this volume is reported in Figure 4A–C.
