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. 2017 Mar 1;13:631–641. doi: 10.2147/NDT.S121448

Table 4.

First-episode characteristics in migraineurs with and without comorbid BD

Characteristics Migraineurs
P-value
With BD (n=23) Without BD (n=97)

n (%) n (%)
First episode
 Mania 1 (4.3) 0 (0.0) 0.059
 Mixed 1 (4.3) 0 (0.0)
 Depression 21 (91.4) 70 (72.1)
 Presence of a life event 20 (87.0) 66 (94.3) 0.358
Severity of episode
 Mild 2 (8.7) 9 (12.9) 0.944
 Moderate 12 (52.2) 36 (51.4)
 Severe 9 (39.1) 25 (35.7)
Associated characteristics
 Postpartum 2 (8.7) 4 (5.7) 0.635
 Catatonic 0 (0.0) 2 (2.9) 1.000
 Melancholic 3 (13.0) 10 (14.3) 1.000
 Atypical 4 (17.4) 11 (15.7) 1.000
 Psychotic 5 (21.7) 3 (4.3) 0.021
Relieved
 Any type 23 (100.0) 70 (100.0)
 Spontaneously 8 (34.8) 22 (31.4) 0.022
 With mood stabilizer 2 (8.7) 1 (1.4)
 With antidepressant 11 (47.8) 47 (67.2)
 With combined therapy 2 (8.7) 0 (0.0)

Notes: χ2 test–Fisher’s exact test–Fisher–Holton–Freeman test. Values in bold indicate statistical significance (P<0.05).

Abbreviation: BD, bipolar disorder.