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. 2017 Feb 28;11:353–362. doi: 10.2147/PPA.S121838

Table 4.

Results of mixed effects logistic regression model for DCE in individuals with psoriasis reporting treatment preferences, stratified by subgroup

Treatment attribute DLQI ≤10, n=166, OR (95% CI) DLQI >10, n=126, OR (95% CI) Biologic therapy experience, n=75, OR (95% CI) Biologic therapy naïve, n=217, OR (95% CI)
BSA (per palm area) 0.90 (0.88–0.93)a 0.97 (0.95–1.00) 0.97 (0.94–1.00) 0.90 (0.88–0.92)a
Increased risk of diarrhea or nausea (per 5% increase) 0.84 (0.79–0.90)a 0.88 (0.82–0.94)a 1.01 (0.93–1.09) 0.79 (0.75–0.85)a
Increased risk of melanoma or nonmelanoma skin cancer (per 5% increased 10-year risk) 0.43 (0.35–0.53)a 0.45 (0.36–0.56)a 0.57 (0.44–0.74)a 0.38 (0.32–0.46)a
Increased risk of tuberculosis (per 5% increased 10-year risk) 0.73 (0.66–0.80)a 0.75 (0.67–0.83)a 0.85 (0.75–0.97)a 0.66 (0.60–0.72)a
Increased risk of serious infection (per 5% increased 10-year risk) 0.70 (0.67–0.72)a 0.79 (0.76–0.81)a 0.87 (0.85–0.90)a 0.70 (0.68–0.72)a
Twice-daily tablet (relative to once-weekly tablet) 0.74 (0.60–0.91)a 0.75 (0.61–0.93)a 0.79 (0.61–1.02) 0.71 (0.59–0.85)a
Weekly injection (relative to once-weekly tablet) 0.48 (0.39–0.61)a 0.72 (0.57–0.90)a 0.84 (0.63–1.11) 0.43 (0.35–0.53)a
Fortnightly injection (relative to once-weekly tablet) 0.49 (0.40–0.60)a 0.86 (0.70–1.06) 0.78 (0.60–1.02) 0.57 (0.48–0.69)a

Note:

a

Attributes significant at the <5% level.

Abbreviations: BSA, body surface area; CI, confidence interval; DCE, discrete choice experiment; DLQI, Dermatology Life Quality Index; OR, odds ratio.