Table 2.

Univariate and multivariate analyses of survival in ESCC

Variable	n	Univariate		Multivariate
		HR (95% CI)	P-value	HR (95% CI)	P-value
Age (years)
≤60	39	1
>60	42	1.473 (0.877–2.472)	0.143
Sex
Male	77	1
Female	4	0.244 (0.034–1.769)	0.163
T stage
pT1–pT2	57	1
pT3–pT4	24	0.981 (0.391–2.459)	0.967
N stage
pN0	45	1		1
pN1–pN2	36	3.196 (1.871–5.460)	<0.001	2.803 (1.626–4.831)	<0.001*
M stage
pM0	79	1
pM1	2	3.101 (0.742–12.971)	0.121
TNM stage
I–II	46	1
III–IV	35	2.477 (1.464–4.192)	0.001*
Differentiation
Good	26	1
Moderate-poor	55	1.475 (0.971–2.239)	0.068
ARHI expression
Low	59	1		1
High	22	0.370 (0.186–0.738)	0.005*	0.458 (0.227–0.924)	0.029*

Note:

^*Statistical significance at P<0.05.

Abbreviations: ARHI, aplysia ras homolog I; HR, hazard ratio; CI, confidence interval; TNM, tumor node metastasis.