Table 1.
Significant genes identified by SAM in carfilzomib-resistant KMS-11 versus parental human myeloma cell line
| Gene ID | Gene name | Fold change | Gene regulation |
|---|---|---|---|
| 202201_at | BLVRB | 3.652113 | Up |
| 219332_at | MICALL2 | 2.988681 | Up |
| 208792_s_at | CLU | 2.831521 | Up |
| 208791_at | CLU | 2.87382 | Up |
| 205943_at | TDO2 | 2.881487 | Up |
| 235343_at | VASH2 | 2.793228 | Up |
| 207469_s_at | PIR | 2.619397 | Up |
| 205081_at | CRIP1 | 2.318266 | Up |
| 244407_at | CYP39A1 | 2.900208 | Up |
| 206140_at | LHX2 | 2.505247 | Up |
| 205348_s_at | DYNC1I1 | 2.19834 | Up |
| 211458_s_at | GABARAPL1 | 2.346701 | Up |
| 223464_at | OSBPL5 | 2.171483 | Up |
| 206435_at | B4GALNT1 | 2.188087 | Up |
| 226884_at | LRRN1 | 2.112008 | Up |
| 227307_at | TSPAN18 | 2.121718 | Up |
| 219740_at | VASH2 | 2.261368 | Up |
| 223633_s_at | BC005081 | 2.245276 | Up |
| 208869_s_at | GABARAPL1 | 2.316713 | Up |
| 203729_at | EMP3 | 2.063944 | Up |
| 217728_at | S100A6 | 2.149586 | Up |
| 232549_at | RBM11 | 2.141973 | Up |
| 219489_s_at | NXN | 2.168232 | Up |
| 222742_s_at | IFT22 | 2.030835 | Up |
| 214453_s_at | IFI44 | 2.126185 | Up |
| 223434_at | GBP3 | 2.010582 | Up |
| 220432_s_at | CYP39A1 | 2.042243 | Up |
| 202983_at | HLTF | 0.24513 | Down |
| 204273_at | EDNRB | 0.261948 | Down |
| 228167_at | KLHL6 | 0.301736 | Down |
| 213478_at | KAZN | 0.367101 | Down |
| 231202_at | ALDH1L2 | 0.318751 | Down |
| 209723_at | SERPINB9 | 0.293765 | Down |
| 204271_s_at | EDNRB | 0.359747 | Down |
| 206701_x_at | EDNRB | 0.320717 | Down |
| 205549_at | PCP4 | 0.398058 | Down |
| 210644_s_at | LAIR1 | 0.395248 | Down |
| 47069_at | PRR5 | 0.447339 | Down |
| 229830_at | Unknown | 0.35393 | Down |
| 205402_x_at | PRSS2 | 0.44509 | Down |
| 215071_s_at | HIST1H2AC | 0.455068 | Down |
| 219259_at | SEMA4A | 0.412331 | Down |
| 213725_x_at | XYLT1 | 0.444801 | Down |
| 205016_at | TGFA | 0.447057 | Down |
| 219168_s_at | PRR5 | 0.444994 | Down |
| 206691_s_at | PDIA2 | 0.466426 | Down |
| 205822_s_at | HMGCS1 | 0.411619 | Down |
| 219255_x_at | IL17RB | 0.456308 | Down |
| 205506_at | VIL1 | 0.472652 | Down |
| 212816_s_at | CBS | 0.459518 | Down |
| 218280_x_at | HIST2H2AA3 | 0.499175 | Down |
| 236451_at | LOC100996579 | 0.431235 | Down |
| 225502_at | DOCK8 | 0.456397 | Down |
| 220565_at | CCR10 | 0.470778 | Down |
| 228821_at | ST6GAL2 | 0.394775 | Down |
| 214455_at | HIST1H2BC | 0.487997 | Down |
| 205463_s_at | PDGFA | 0.469407 | Down |
| 205898_at | CX3CR1 | 0.433747 | Down |
| 209598_at | PNMA2 | 0.454474 | Down |
| 216470_x_at | PRSS2 | 0.46771 | Down |
| 224156_x_at | IL17RB | 0.498466 | Down |
| 208962_s_at | FADS1 | 0.484027 | Down |
| 225846_at | ESRP1 | 0.482879 | Down |
Abbreviation: SAM, Significant Analysis of Microarray.