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ZnO NPs induce ROS in a dose-dependent manner in the midgut of the Drosophila melanogaster larvae.
Notes: (A) DHE stain in control gut shows the basal level of ROS. (B, C) Treated gut cells show a gradual increase in DHE intensity. In particular, a dramatic increase in ROS is detected in gut cells treated with ZnO NPs at 0.5 mg/mL.
Abbreviations: DAPI, 4′,6-diamidino-2-phenylindole; DHE, dihydroethidium; ROS, reactive oxygen species; NPs, nanoparticles.
