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. 2016 Dec 7;123(6):1061–1070. doi: 10.1002/cncr.30437

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© 2016 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Patient risk and overall survival as assessed by Met IHC expression. (A) Cox proportional hazards model evaluation of IHC classification with respect to overall survival. HRs along with 95% CIs comparing Met‐positive and Met‐negative patients at each cutoff value are depicted. (B,C) Kaplan‐Meier curves depicting the overall survival of the subjects by the Met IHC status with cutoffs of (B) 25% and (C) 50%. (D) Cox proportional hazards model evaluation of the IHC status with respect to overall survival. A multivariate analysis was performed, and 25% staining was used as the Met‐positive cutoff. HRs along with 95% CIs for each baseline covariate are depicted. CI indicates confidence interval; EGJ, esophagogastric junction; HER2, human epidermal growth factor receptor 2; HR, hazard ratio; IHC, immunohistochemistry; SRM, selected reaction monitoring.