Table 2. Demographic, clinical, laboratory, and thromboelastographic characteristics of patients and controls.
| Non-cirrhotic group (N = 52) | Cirrhotic group (N = 123) | Control group (N = 84) | ||
|---|---|---|---|---|
| Age (yr) | 55.0 (24–78) | 59.0 (31–82) | 55.0 (20–78) | |
| Female (%) | 71.2 | 28.7 | 46.4 | |
| Etiology | Viral | 26 | 76 | NA |
| PBC | 12 | 5 | NA | |
| Autoimmune | 9 | 1 | NA | |
| Alcohol | 1 | 30 | NA | |
| Other | 4 | 11 | NA | |
| PT (INR) | 1.03 (0.78–3.76)† | 1.23 (0.94–7.05)* | 0.97 (0.88–1.15) | |
| Hemoglobin (g/dL) | 13.4 (9.9–17.6)*,† | 11.7 (5.3–16.3)* | 13.5 (9.4–18.6) | |
| Platelet (× 109/L) | 188.0 (84–328)*,† | 113.0 (29–499)* | 243.0 (123–431) | |
| TEG parameters | R (min) | 4.2 (2.2–9.8) | 4.8 (0.2–8.6)* | 4.2 (0.2–6.8) |
| K (min) | 1.8 (0.9–7.8)† | 2.0 (0.8–12.3)* | 1.7 (0.8–5.9) | |
| α (degree) | 65.8 (28.4–76.0)† | 63.3 (27.2–79.5)* | 67.1 (35.1–77.5) | |
| MA (mm) | 57.1 (28.4–68.7)*,† | 50.2 (21–75.5)* | 59.9 (32.9–74.1) | |
| CI | 0.6 (–9.3–3.6)† | –0.8 (–9.8–6.4)* | 1.3 (–7.4–6.0) |
Values are expressed as tmedians and ranges.
*P<0.05 indicates a significant difference between each group and the control group; †P<0.05 indicates a significant difference between the non-cirrhotic and cirrhotic groups.
Abbreviations: NA, not applicable; PBC, primary biliary cirrhosis; PT, prothrombin time; INR, international normalized ratio; TEG, thromboelastography; R, reaction time; K, kinetic time; α, α-angle; MA, maximum amplitude; CI, coagulation Index.