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. 2016 Oct 5;475(4):1080–1099. doi: 10.1007/s11999-016-5098-3

Fig. 1A–B.

Fig. 1A–B

(A) A schematic drawing of intact biochemical cartilage composition is shown. (B) A degenerated cartilage is characterized by a loss of GAG and collagen and an increase of water. The negatively charged gadolinium molecules replace the lost GAGs, which can be measured with MRI.