Table 3.
Comparison among the results of histopathological, histochemical and molecular studies in the different groups
| Item | Group | ||||
|---|---|---|---|---|---|
| G2 | G3 | G4 | G5 | G6 | |
| Granuloma no. | 69.17 ± 12.5 | 64.5 ± 12.1 | 25.33 ± 5.96*** | 28.66 ± 6.5*** | 7.67 ± 2.16*** |
| Granuloma size | 357.33 ± 53.08 | 341 ± 31.95 | 223.17 ± 14.12 *** | 241.5 ± 18.29 *** | 164.67 ± 17.95 *** |
| Apoptosis by Feulgen | Severe | Severe | Moderate | Moderate | Mild |
| −ve fragmentation | 0 % | 0 % | 16.7 % | 33.3 % | 33.3 % |
| Mild fragmentation | 0 % | 0 % | 33.3 % | 33.3 % | 66.7 % |
| Moderate fragmentation | 0 % | 33.3 % | 50 % | 16.7 % | 0 % |
| Severe fragmentation | 100 % | 66.7 % | 0 % | 16.7 % | 0 % |
*** Very high significant difference from infected control at p < 0.001