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. 2017 Mar 7;11:6. doi: 10.3389/fnint.2017.00006

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Copyright © 2017 Chang, Turuwhenua, Qu, Black and Acosta.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pupillary light reflex (PLR) response in juvenile and adult female and male guinea pigs. (A) Resting pupil diameter was equivalent in males and females except for the younger female age group. (B) Constriction velocity (CV) was significantly lower in the adult guinea pigs. (C) The constriction ratio was higher only different in the adult female group. (D) Re-dilation velocity (DV) showed no differences except for the juvenile female group. Statistical values were obtained using analysis of variance (ANOVA); asterisks indicate: *p < 0.05, **p < 0.01, ***p < 0.001.