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. 2017 Mar 7;11:64. doi: 10.3389/fncel.2017.00064

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Copyright © 2017 Song, Choi and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of CD86 and Iba-1 in 5xFAD mouse brain. (A) Western blotting band showed increased CD86 protein level in the 5xFAD mouse brain. Data are expressed as mean ± SEM. Each experiment was conducted three times per condition. β-actin served as a control. Differences were considered statistically significant at *p < 0.05 (compared to control). Immunofluorescence images showed increased expression of CD86 (B) and Iba-1 (C) in the cortex and striatum of the 5xFAD mouse brain. Scale bar: 50 μm, Con: normal mouse, 5xFAD: 5xFAD mouse, CD86: green, Iba-1: green, 4′,6-diamidino-2-phenylindole (DAPI): blue.