Figure 2.

The expression of CD86 and CD206 in amyloid beta (Aβ)-treated BV2 microglia. The mRNA level of CD86 (A) and CD206 (B) was detected by RT PCR. Data are expressed as mean ± SEM. Each experiment was conducted three times per condition. GAPDH served as a control. Differences were considered statistically significant at *p < 0.05 (compared to control). (C) Immunofluorescence images showed the reduction of CD86 by Acrp30 pretreatment in Aβ- exposed BV2 microglia. Acrp30: Acrp30 5 μg/ml pretreatment, Aβ: Aβ 10 μM treatment for 24 h, Scale bar: 100 μm, CD86: green, 4′,6-diamidino-2-phenylindole (DAPI): blue.