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. 2017 Mar 7;11:67. doi: 10.3389/fncel.2017.00067

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Copyright © 2017 Yu, Wang, Zhao, Zhang, Tao, Shi, Sun and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sodium hydrosulfide treatment (250 μM) could significantly repair OGD-induced injuries of neurite sprouting and outgrowth in the young and aged hippocampal neurons in 7 DIV. (A) Typical hippocampal neurons with extending neurites in the cultures, stained for MAP-2. Scale bar = 40 μm. The neurite sprouting and outgrowth were analyzed by the number of primary dendrites per cell (B), the number of dendritic end tips (C), and the average neurite length (D). Data were presented by the mean ± SD. ^∗p < 0.05 and ^∗∗p < 0.01 versus corresponding control, ^##p < 0.01 versus corresponding OGD group.