Table 1.
Controls (cognition) | Controls (imaging) | ALS patients | p | |
---|---|---|---|---|
Main features of the participants | ||||
Age (years) | 61.81 | 59 | 61.83 | 0.83 (cognition)/0.91 (imaging) |
Sex (F/M) | 16/21 | 16/21 | 16/21 | |
Years of education | 11.11 | 11.43 | 9.92 | 0.070 (cognition)/0.099 (imaging) |
Mattis (total) | 139.95 | 141 | 136.47 | 0.005 (cognition)/<0.001 (imaging) |
ALSFRS-R score | / | / | 37.31 | |
Cognitive profile | ||||
TMT (B–A) | 15.94 | 62.97 | <0.001 | |
Letter verbal fluency score | 22.24 | 15.03 | <0.001 | |
Letter verbal fluency index | 4.71 | 7.68 | 0.017 | |
Episodic memory | 12.14 | 7.08 | <0.001 | |
Cognitive theory of mind | 13.22 | 11.36 | 0.009 | |
Affective theory of mind | 12.44 | 11.03 | 0.062 |