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Site of first recurrence
| Stage | Total patients | Total recurrence | Locoregional | Systemic |
|---|---|---|---|---|
| Stage II | 115 | 54 | 28 (52%) | 26(48%) |
| Stage III | 328 | 158 | 50 (32%) | 108 (68%) |
| Stage IV | 23 | 13 | 3 (23%) | 10 (77%) |
| Total | 466 | 225 | 81 (36%) | 144 (64%) |
Locoregional is defined as local, in-transit, and nodal metastases
