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. 2017 Feb 7;15(1):37–48. doi: 10.1016/j.gpb.2016.12.002

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© 2017 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The fusion gene IGLV2-14-IGLL5 detected in monozygotic twin brothers with PMF

A. A representative fusion gene of IGLV2-14-IGLL5 on chromosome 22 was detected from transcriptomic sequencing data. B. The IGLV2-14-IGLL5 fusion gene was confirmed by PCR amplification. M represents marker. The expected size of 378 bp is marked with an arrow. C. The Sanger sequencing profiles for three samples. The break points were marked with a vertical line. E1 and E2 denote the elder brother before and after treatment, respectively, and Y2 denotes the younger brother after treatment.