FIG. 4.
Recombination crossover points in PERV-A/C hybrid env genes. Six nucleotide sequences of env genes (NIH, accession no. AF130444 [55]; T2A3, AF417230; T2A5, AF417231; T6E5, AF417232; T12C9, AF417229; T1428, AY364236 [28]) and three env coding sequences extracted from A14/220, Cmsl, and A130 (their lengths are between 1,917 nt of Cmsl and 1,983 nt of A130), were analyzed by LOHATM with a window size of 21 nt. Homology plots of Cmsl against seven A/C recombinant sequences are shown (1,984 nt positions in the alignment [x axis]; 0, 10, 20, 30, 40, 50, or 60% was subtracted from percent match values as indicated [y axis]). A plot of Cmsl versus A130 is also shown (percent match, 100 [y axis]). The apparent crossover points from PERV-A- to PERV-C-like sequence are indicated by arrows.