Table 2.
Comparison of clinical, laboratory, echocardiographic, and central hemodynamic variables of congestion among patients enrolled in the ESCAPE trial who have positive or negative hepatojugular reflux on discharge.
| +ve HJR on discharge (n = 115) |
−ve HJR on discharge (n = 277) |
P value | |
|---|---|---|---|
| Clinical and laboratory variables of congestion | |||
| JVD at discharge >8 cm % (n) | 57.5% (65/113) | 25.9% (68/263) | <0.001 |
| At least moderate ascites % (n) | 9.6% (11/115) | 1.1% (3/276) | 0.001 |
| Hepatomegaly % (n) | 40.9% (47/115) | 8.9% (24/271) | <0.001 |
| Rales % (n) | 16.5% (19/115) | 5.8% (16/277) | 0.001 |
| BNP (pg/mL, m ± SD) | 936 ± 1428 | 659 ± 1041 | 0.002 |
|
| |||
| Echocardiography variables of congestion | |||
| IVC size in inspiration (cm, m ± SD) | 1.5 ± 0.73 | 1.1 ± 0.78 | 0.005 |
| IVC size in expiration (cm, m ± SD) | 2.1 ± 0.67 | 1.8 ± 0.7 | 0.003 |
|
| |||
| PAC data at final hemodynamic measurement | |||
| RAP (mmHg, m ± SD) | 11.1 ± 6.5 | 7.8 ± 4.2 | 0.002 |
| PASP (mmHg, m ± SD) | 49.9 ± 13 | 43.9 ± 11.6 | 0.005 |
| PADP (mmHg, m ± SD) | 23.2 ± 8.2 | 20 ± 6.2 | 0.009 |
| PAMP (mmHg, m ± SD) | 32.3 ± 11.5 | 28.3 ± 7.8 | 0.01 |
| PCWP (mmHg, m ± SD) | 19.8 ± 8 | 16.1 ± 6 | 0.006 |
HJR: hepatojugular reflux; JVD: jugular venous distension; BNP: B-type natriuretic peptide; IVC: inferior vena cava; RAP: right atrial pressure; PASP: pulmonary artery systolic pressure; PADP: pulmonary artery diastolic pressure; PAMP: pulmonary artery mean pressure; PCWP: pulmonary capillary wedge pressure.