Table 3.
Sensitivity and specificity of miR-132-3p and number of true positive, true negative, false positive, and false negative tests, calculated for maximum Youden's Index (YI) and fixed false positive rates (FPRs) of 0%, 5%, and 10%.
FPR (%) | Cut-off | Sensitivity (%) | Specificity (%) | True positive (N) | True negative (N) | False positive (N) | False negative (N) |
---|---|---|---|---|---|---|---|
2−(miR-132-3p - miR-146b) | |||||||
Maximum YI | 0.100 | 86 | 61 | 19 | 27 | 17 | 3 |
0 | 0.014 | 5 | 100 | 1 | 44 | 0 | 21 |
5 | 0.047 | 23 | 95 | 5 | 42 | 2 | 17 |
10 | 0.063 | 36 | 90 | 8 | 39 | 5 | 14 |