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. 2016 Aug 16;70(3):255–259. doi: 10.1136/jclinpath-2016-203874

Table 2.

Categorisation of MBCs based on PD-L1 expression in tumour cells and low or high PD-1 expression in TILs

Type Tumour microenvironment
(PD-L1/PD-1 TILs)
Number of cases
(n=71)
1 PD-L1 positive, high PD-1* 16 (23%)
2 PD-L1 negative, low PD-1* 22 (31%)
3 PD-L1 positive, low PD-1* 14 (20%)
4 PD-L1 negative, high PD-1* 19 (26%)

*PD-1 categorisation as high or low is done around the median of 22.5.

MBC, metaplastic breast carcinoma; PD-1, programmed cell death 1; PD-L1; programmed death-ligand 1; TIL, tumour infiltrating lymphocyte.