Table 2.

Volume sizes relative to eTIV for patient and control groups.

	Group 1		p	Group 2		p	Group 3		p
	HC	MCI-S		HC	MCI-CB		HC	MCI-CC
eTIV, cm3	1586.33 177.35	1546.71 155.10	0.424	1499.99 155.00	1498.05 133.58	0.976	1487.72 132.59	1507.66 133.52	0.741
Hippocampus total, left	0.14206 0.01670	0.13915 0.02510	0.670	0.14995 0.01635	0.11236 0.013455	0.000*	0.14493 0.00780	0.10656 0.01278	0.000*
Subiculum	0.02103 0.00250	0.01972 0.00379	0.162	0.02210 0.00243	0.01650 0.00230	0.000*	0.02060 0.00222	0.01579 0.00260	0.000*
CA1	0.04545 0.00509	0.04568 0.00773	0.872	0.04834 0.00525	0.03648 0.00436	0.000*	0.04651 0.00348	0.03587 0.00509	0.000*
CA2-CA3	0.00851 0.00180	0.00849 0.00200	0.966	0.00882 0.00184	0.00752 0.00154	0.088	0.00904 0.00088	0.00659 0.00162	0.001*
CA4/Dentate gyrus	0.03399 0.00460	0.03264 0.00611	0.415	0.03594 0.00464	0.02756 0.00380	0.000*	0.03500 0.00282	0.02583 0.00354	0.000*
Strata	0.03308 0.00449	0.03262 0.00682	0.821	0.03475 0.00417	0.02428 0.00335	0.000*	0.03377 0.00247	0.02249 0.00255	0.000*
Hippocampus total, right	0.14140 0.01557	0.14454 0.01796	0.495	0.14991 0.01238	0.12429 0.02027	0.001*	0.14467 0.00825	0.11796 0.01651	0.000*
Subiculum	0.01936 0.00235	0.01907 0.00326	0.753	0.02079 0.00254	0.01677 0.00321	0.005*	0.01998 0.00258	0.01590 0.00277	0.001*
CA1	0.04698 0.00538	0.04862 0.00607	0.335	0.05002 0.00413	0.04260 0.00668	0.005*	0.04862 0.00335	0.04165 0.00626	0.005*
CA2-CA3	0.00926 0.00125	0.00958 0.00162	0.449	0.00961 0.00135	0.00848 0.00195	0.068	0.00933 0.00179	0.00750 0.00210	0.044*
CA4/Dentate gyrus	0.03396 0.00414	0.03464 0.00396	0.519	0.03560 0.00418	0.02973 0.00471	0.002*	0.03426 0.00261	0.02795 0.00360	0.000*
Strata	0.03184 0.00438	0.03263 0.00516	0.534	0.03377 0.00266	0.02671 0.00517	0.000*	0.03249 0.00237	0.02497 0.00398	0.000*
Thalamus total, left	0.32430 0.02209	0.32525 0.02228	0.882	0.33248 0.01846	0.32428 0.02484	0.433	0.32998 0.02614	0.31843 0.02588	0.431
LGN	0.00705 0.00084	0.00701 0.00066	0.894	0.00727 0.00159	0.00688 0.00119	0.475	0.00713 0.00085	0.00658 0.00115	0.220
MGN	0.01009 0.00150	0.10103 0.00082	0.898	0.01017 0.00133	0.00965 0.00126	0.320	0.01081 0.00133	0.00981 0.00114	0.106
Anterior nuclei	0.00548 0.00092	0.00539. 00086	0.665	0.00531 0.00057	0.00555 0.00087	0.328	0.00533 0.00072	0.00575 0.00100	0.257
Central nuclei	0.01578 0.00014	0.01538 0.00151	0.447	0.01597 0.00137	0.01500 0.00143	0.158	0.01624 0.00188	0.01491 0.00165	0.177
Lateral dorsal nuclei	0.00276 0.00073	0.00295 0.00080	0.418	0.00283 0.00074	0.00324 0.00054	0.086	0.00307 0.00072	0.00332 0.00069	0.252
Lateral posterior nuclei	0.02229 0.00299	0.02363 0.00275	0.128	0.02276 0.00238	0.02432 0.00167	0.108	0.02363 0.00197	0.02401 0.00233	0.695
Medial dorsal nuclei	0.05222 0.00562	0.05085 0.00544	0.415	0.05292 0.00427	0.05046 0.00626	0.336	0.05276 0.00650	0.04920 0.00605	0.290
Pulvinar	0.07683 0.00768	0.07732 0.00654	0.798	0.07540 0.00570	0.07350 0.00848	0.565	0.07474 0.00625	0.07162 0.00742	0.556
VA	0.03156 0.00297	0.03175 0.00404	0.868	0.03288 0.00229	0.03343 0.00302	0.550	0.03199 0.00340	0.03234 0.00350	0.979
VP	0.02520 0.00265	0.02484 0.00230	0.631	0.02593 0.00264	0.02329 0.00244	0.015	0.02547 0.00208	0.02202 0.00264	0.009
VL	0.04554 0.00444	0.04591 0.00551	0.810	0.04858 0.00363	0.04578 0.00585	0.156	0.04691 0.00351	0.04434 0.00674	0.268
Thalamus total, right	0.32413 0.02336	0.32019 0.02076	0.567	0.33124 0.01278	0.31827 0.02027	0.083	0.32838 0.02470	0.31547 0.02189	0.257
LGN	0.01136 0.00138	0.01143 0.00134	0.861	0.01190 0.00125	0.01203 0.002108	0.947	0.01177 0.00096	0.01160 0.00211	0.626
MGN	0.01235 0.00142	0.01226 0.00109	0.790	0.01268 0.00096	0.01262 0.00148	0.875	0.01314 0.00120	0.01264 0.00181	0.581
Anterior nuclei	0.00759 0.00109	0.00720 0.00146	0.283	0.00749 0.00070	0.00792 0.00068	0.209	0.00787 0.00099	0.00796 0.00055	0.912
Central nuclei	0.00979 0.00084	0.00948 0.00078	0.218	0.01003 0.00060	0.00968 0.00075	0.237	0.01021 0.00117	0.00960 0.00073	0.224
Lateral dorsal nuclei	0.00309 0.00089	0.00296 0.00077	0.570	0.00299 0.00058	0.00329 0.00064	0.180	0.00302 0.00063	0.00334 0.00060	0.084
Lateral posterior nuclei	0.01683 0.00247	0.01672 0.00216	0.886	0.01594 0.00158	0.01687 0.00132	0.213	0.01708 0.00147	0.01680 0.00124	0.988
Medial dorsal nuclei	0.04785 0.00373	0.04630 0.00452	0.226	0.04823 0.00430	0.04647 0.00435	0.370	0.04928 0.00685	0.04610 0.00474	0.222
Pulvinar	0.09388 0.00827	0.09504 0.00743	0.569	0.09443 0.00553	0.08914 0.00799	0.114	0.09228 0.00659	0.08769 0.00847	0.307
VA	0.03362 0.00285	0.03242 0.00400	0.246	0.03532 0.00326	0.03405 0.00280	0.261	0.03404 0.00323	0.03352 0.00297	0.509
VP	0.03795 0.00441	0.02331 0.00260	0.753	0.02382 0.00180	0.02196 0.00257	0.047	0.02337 0.00163	0.02135 0.00253	0.054
VL	0.03876 0.00349	0.03715 0.00435	0.221	0.04071 0.00302	0.03818 0.00468	0.109	0.03925 0.00388	0.03786 0.00485	0.339
Striatum total, left	0.51914 0.03450	0.49659 0.02327	0.013*	0.51636 0.03540	0.50261 0.03202	0.482	0.49783 0.02986	0.50050 0.03693	0.936
Striatum total, right	0.51211 0.03543	0.48445 0.02920	0.006*	0.50521 0.03297	0.49679 0.02506	0.557	0.49142 0.02774	0.49558 0.02767	0.917

Values represent means and standard deviations of volumes relative to estimated total incranial volume ^*100. HC, healthy control subjects; MCI-S, stable mild cognitive impairment at baseline; MCI-CB, mild cognitive impairment converters at baseline; MCI-CC, mild cognitive impairment converters at time of conversion; eTIV, estimated total intracranial volume; CA, cornu ammonis; LGN, lateral geniculate nucleus; MGN, medial geniculate nucleus; VA, ventral anterior nuclei; VP, ventral posterior nuclei; VL, ventral lateral nuclei.

^*Significant p value test by using volumes relative to estimated total intracranial volume and multiplied by 100 as dependent variables, and including age and gender in the model, and after correction for multiple testing.