Table 4.
Reduced cortical thickness in patient groups.
| Anatomic localization | MNI coordinates (peak) | t statistic (peak) | ||
|---|---|---|---|---|
| x | y | z | ||
| A | ||||
| Parahippocampal Cortex, left | −30 | −16 | −27 | −5.77** |
| Subgenual Cingulate, left | −18 | 15 | −14 | −4.34** |
| Uncus, left | −29 | −29 | −8 | −6.53** |
| B | ||||
| Parahippocampal Cortex, left | −25 | −13 | −32 | −7.13** |
| Uncus, left | −31 | −12 | −23 | −7.06** |
| Parahippocampal Cortex, right | 29 | −12 | −28 | −5.45* |
| Uncus, right | 31 | −10 | −22 | −5.20* |
Anatomical localization of cortical thinning in mild cognitive impairment converters at baseline (A), and in mild cognitive impairment converters at time of conversion (B). MNI: Montreal Neurological Institute.
significant after including age and gender in the model, and after correction using False Discovery Rate at q < 0.10.
significant after including age and gender in the model, and after correction using False Discovery Rate at q < 0.01.