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. 2017 Jan;6(1):62–67.

Fig. 2:

Chondrogenic gene expression Sox9, AGG ،Col2A, COMP, Link P, MMP13, Runx2, Col1, ALP, Col10 in attached and float chondrons at day 7. A) Sox9 gene expression in attached and float chondrons at day 7. High gene expression of Sox9 in float chondrons versus attached chondrons (p<0.05). (B) Col2A gene expression in attached and float chondrons at day 7C). AGG gene expression in attached and float chondrons at day 7. D) Link P gene expression in attached and float chondrons at day 7. E) COMP gene expression in attached and float chondrons at day 7.

Fig. 2:

Decreasing of COMP gene expression in attached chondrons were significant versus float chondrons (p<0.0005). F) Runx2 gene expression in attached and float chondrons at day 7. Increasing of Runx2 gene expression in attached chondrons were significant versus float chondrons (p<0.05). G). Col1 gene expression in attached and float chondrons at day 7. Increasing of Col1 gene expression in attached chondrons were significant versus float chondrons (p<0.05). H) Col10 gene expression in attached and float chondrons at day 7.

Decreasing of Col10 gene expression in attached chondrons were significant versus float chondrons (p<0.05). Values are mean ± SEM, n=3. Sox9, SRY (sex determining region Y)-box 9; Col2A, collagen type 2A; AGG, aggrecan; COMP, cartilage oligomeric matrix protein; Link P, Link protein; Col1, collagen type I; Runx2, runt-related transcription factor-2; MMP13, matrix metalloproteinase-13; ALP, alkaline phosphatase; Col10, collagen type 10.